Description:
Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM, respectively.
- Molecular Weight: 530.45
- Molecular Formula: C26H29Cl2N5O3
Purity: >98%
Canonical SMILES:
CN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)OC)C#N)OC
InChI:
InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)
InChIKey: UBPYILGKFZZVDX-UHFFFAOYSA-N
- Boiling Point: 649.7±55.0 °C at 760 mmHg
- Melting Point: 116-120 °C
- Solubility: Soluble in DMSO
- Appearance: Pale Yellow Solid
- Storage: Store at RT
Synonyms:
3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-; 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile; Bosulif; KIN 001-160; SK 606; SKI 606; SKI606; SK-I606
More details are to be found on supplier website
